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Published Papers

Below is a sample of published papers describing work wholly or partly funded by Action Against Cancer. Please click to enlarge the samples.

  1. PDGF-R inhibition induces glioblastoma cell differentiation via DUSP1/p38MAPK signalling
  2. Definition of an Inflammatory Biomarker Signature in Plasma-Derived Extracellular Vesicles of Glioblastoma Patients
  3. Tuneable synthetic reduced graphene oxide scaffolds elicit high levels of three-dimensional glioblastoma interconnectivity in vitro
  4. Reconstituting Immune Surveillance in Breast Cancer: Molecular Pathophysiology and Current Immunotherapy Strategies
  5. The multifaceted role of lemur tyrosine kinase 3 in health and disease
  6. LMTK3 inhibition affects microtubule stability
  7. Protein kinases play a pivotal role in regulating intracellular signal transduction
  8. Cell-derived extracellular vesicles can be used as a biomarker reservoir for glioblastoma tumor subtyping
  9. TGF-β induces miR-100 and miR-125b but blocks let-7a through LIN28B controlling PDAC progression
  10. LMTK3 confers chemo-resistance in breast cancer
  11. microRNAs with prognostic significance in pancreatic ductal adenocarcinoma: A meta-analysis, European Journal of Cancer
  12. LMTK3 Represses Tumor Suppressor-like Genes through Chromatin Remodeling in Breast Cancer, ECell Reports
  13. Characterization of the Tyrosine Kinase-Regulated Proteome in Breast Cancer by Combined use of RNA interference (RNAi) and Stable Isotope Labeling with Amino Acids in Cell Culture (SILAC) Quantitative Proteomics, Molecular & Cellular Proteomics
  14. Whole Genome Sequence Analysis Suggests Intratumoral Heterogeneity in Dissemination of Breast Cancer to Lymph Nodes, PLOS One
  15. The prognostic role of circulating tumor cells in heavily pretreated individuals with a low life expectancy, Future Oncology
  16. ATG9A Loss Confers Resistance to Trastuzumab via c-CbI mediated Her2 Degradation, Oncotarget
  17. Strategies in functional proteomics: Unveiling the pathways to precision oncology, Cancer Letters
  18. Investigating miRNA-mRNA regulatory networks using crosslinking immunoprecipitation methods for biomarker and target discovery in cancer, Expert Review of Molecular Diagnostics
  19. Noncoding RNAs and the control of signalling via nuclear receptor regulation in health and disease, Best Practice & Research Clinical Endocrinology & Metabolism
  20. Proteome-wide dataset supporting functional study of tyrosine kinases in breast cancer, Data in Brief
  21. Sustained expression of miR-26a promotes chromosomal instability and tumorigenesis through regulation of CHFR, Nucleic Acids Research
  22. Prospective Validation of microRNA Signatures for Detecting Pancreatic Malignant Transformation in Endoscopic-Ultrasound Guided Fine-Needle Aspiration Biopsies, Oncotarget
  23. LMTK3 escapes tumour suppressor miRNAs via sequestration of DDX5, Cancer Letters
  24. microRNAs with prognostic significance in pancreatic ductal adenocarcinoma: A meta-analysis, European Journal of Cancer