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Published Papers

Below is a sample of published papers describing work wholly or partly funded by Action Against Cancer. Please click to enlarge the samples.

  1. Spatial biology – unravelling complexity within the glioblastoma microenvironment
  2. Preserving Fossilized Soft Tissues: Advancing Proteomics and Unveiling the Evolutionary History of Cancer in Dinosaurs
  3. Unlocking the diagnostic power of plasma extracellular vesicle miR-200 family in pancreatic ductal adenocarcinoma
  4. Kinome-Wide Synthetic Lethal Screen Identifies PANK4 as aModulator of Temozolomide Resistance in Glioblastoma
  5. A bile-based microRNA signature for differentiating malignant from benign pancreaticobiliary disease
  6. The role of non-coding RNAs in extracellular vesicles in breast cancer and their diagnostic implications
  7. Comparison of phenomics and cfDNA in a large breast screening population: the Breast Screening and Monitoring Study (BSMS)
  8. Comparison of phenomics and cfDNA in a large breast screening population: the Breast Screening and Monitoring Study (BSMS)
  9. The Inhibitory Properties of a Novel, Selective LMTK3 Kinase Inhibitor
  10. Incorporating Immunotherapy in the Management of Gastric Cancer: Molecular and Clinical Implications
  11. LncRNAs in breast cancer: a link to future approaches
  12. PDGF-R inhibition induces glioblastoma cell differentiation via DUSP1/p38MAPK signalling
  13. Definition of an Inflammatory Biomarker Signature in Plasma-Derived Extracellular Vesicles of Glioblastoma Patients
  14. Tuneable synthetic reduced graphene oxide scaffolds elicit high levels of three-dimensional glioblastoma interconnectivity in vitro
  15. Reconstituting Immune Surveillance in Breast Cancer: Molecular Pathophysiology and Current Immunotherapy Strategies
  16. The multifaceted role of lemur tyrosine kinase 3 in health and disease
  17. LMTK3 inhibition affects microtubule stability
  18. Protein kinases play a pivotal role in regulating intracellular signal transduction
  19. Cell-derived extracellular vesicles can be used as a biomarker reservoir for glioblastoma tumor subtyping
  20. TGF-β induces miR-100 and miR-125b but blocks let-7a through LIN28B controlling PDAC progression
  21. LMTK3 confers chemo-resistance in breast cancer
  22. microRNAs with prognostic significance in pancreatic ductal adenocarcinoma: A meta-analysis, European Journal of Cancer
  23. LMTK3 Represses Tumor Suppressor-like Genes through Chromatin Remodeling in Breast Cancer, ECell Reports
  24. Characterization of the Tyrosine Kinase-Regulated Proteome in Breast Cancer by Combined use of RNA interference (RNAi) and Stable Isotope Labeling with Amino Acids in Cell Culture (SILAC) Quantitative Proteomics, Molecular & Cellular Proteomics
  25. Whole Genome Sequence Analysis Suggests Intratumoral Heterogeneity in Dissemination of Breast Cancer to Lymph Nodes, PLOS One
  26. The prognostic role of circulating tumor cells in heavily pretreated individuals with a low life expectancy, Future Oncology
  27. ATG9A Loss Confers Resistance to Trastuzumab via c-CbI mediated Her2 Degradation, Oncotarget
  28. Strategies in functional proteomics: Unveiling the pathways to precision oncology, Cancer Letters
  29. Investigating miRNA-mRNA regulatory networks using crosslinking immunoprecipitation methods for biomarker and target discovery in cancer, Expert Review of Molecular Diagnostics
  30. Noncoding RNAs and the control of signalling via nuclear receptor regulation in health and disease, Best Practice & Research Clinical Endocrinology & Metabolism
  31. Proteome-wide dataset supporting functional study of tyrosine kinases in breast cancer, Data in Brief
  32. Sustained expression of miR-26a promotes chromosomal instability and tumorigenesis through regulation of CHFR, Nucleic Acids Research
  33. Prospective Validation of microRNA Signatures for Detecting Pancreatic Malignant Transformation in Endoscopic-Ultrasound Guided Fine-Needle Aspiration Biopsies, Oncotarget
  34. LMTK3 escapes tumour suppressor miRNAs via sequestration of DDX5, Cancer Letters
  35. microRNAs with prognostic significance in pancreatic ductal adenocarcinoma: A meta-analysis, European Journal of Cancer

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